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Mononucleosis (Mono)

Also Known As: Monospot, Mononuclear Spot test, Mononucleosis Spot Test, Mono Test, Heterophile Antibody Test, Heterophile Antibody Assay, Heterophile Test, Heterophile Agglutination Test, Infectious Mononucleosis Rapid Test

Infectious mononucleosis, or mono, is a disease most frequently caused by infection with the Epstein-Barr virus (EBV). The viruses that cause mono are commonly spread through bodily fluids, especially saliva. While less common, transmission may also occur through blood and semen during sexual contact, blood transfusions, and organ transplantations.

Several tests may be used to confirm a diagnosis of infectious mononucleosis, including mononucleosis testing, also called heterophile antibody testing. Mononucleosis testing is performed with a blood sample and looks for specific substances that form in the body during the infection.

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