Aspartate Aminotransferase (AST)

Aspartate aminotransferase (AST) is an enzyme, a type of protein that enables most bodily processes. AST exists mostly in the liver, but it is found in numerous tissues in the body.

When cells become damaged, AST can be released into the bloodstream. For this reason, abnormal levels of AST in a blood sample can indicate an underlying problem.

Although AST can be measured alone, it is usually included with other enzymes as part of broader tests, such as a liver panel or comprehensive metabolic panel (CMP). When interpreted alongside other enzymes, an AST measurement can help identify liver disease and other health issues.